Surgical treatment of retroperitoneal leiomyosarcoma with adjuvant radiotherapy.

Received April 2007 Accepted June 2007 INTRODUCTION Although leiomyosarcoma is among the most common nonepithelial retroperitoneal tumors along with fibrosarcoma, liposarcoma, and malignant lymphoma, it only constitutes 5% to 15% of all retroperitoneal tumors. About 70% of leiomyosarcomas are found in the retroperitoneal space.(1) Extensive surgical resection for achieving complete removal and providing negative surgical margins is the treatment of choice. This is also the most important factor in preventing local recurrence.(2-4) We present 2 cases with retroperitoneal leiomyosarcomas invading the inferior vena cava and the ureter. Preoperative workup was made for complete resection and achieving negative margins. Adjuvant radiotherapy was administered following surgical therapy to decrease the risk of local recurrence. CASE REPORT